Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before...
Read More »Researchers use single-cell RNA sequencing to map changes in immune microenvironment in myeloma precursor conditions
Results are step toward personalized treatment of myeloma and precursors based on immune microenvironment in patients’ bone marrow Long before multiple myeloma becomes a malignant disease...
Read More »The combination of WGS and RNA-Seq is superior to conventional diagnostic tests in multiple myeloma
The diagnosis and risk stratification of multiple myeloma (MM) is based on clinical and cytogenetic tests. Magnetic CD138 enrichment followed by interphase FISH (fluorescence in situ hybridisation) is the...
Read More »The unique genetic makeup of myeloma tumor cells revealed by single cell RNA-Seq
Cancer arises when cells lose control. Deciphering the "blueprint" of cancer cells - outlining how cancer cells hijack specific pathways for uncontrolled proliferation - will lead to more efficient ways to fight it. Joint effort of scientists from the Weizmann Institute of Science and clinicians from major hemato-oncology departments in Israel succeeded...
Read More »RNA sequencing can contribute to the development of a reliable drug recommendation tool
A new precision medicine platform utilizing both DNA and RNA sequencing helps identify targeted therapy options for patients with relapsed or refractory multiple myeloma. Multiple myeloma (MM) is a malignancy of plasma cells, with a median survival...
Read More »Single cell RNA sequencing and multiple myeloma
This Center for Evolution and Medicine Seminar features Nicholas Banovich, Assistant Professor in the Integrated Cancer Genomics Division at the Translational Genomics Research Institute...
Read More »Single cell RNA sequencing and Multiple Myeloma
This Center for Evolution and Medicine Seminar features Nicholas Banovich, Assistant Professor in the Integrated Cancer Genomics Division at the Translational Genomics Research Institute.
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