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N6-methyladenosine (m6A) is an abundant RNA modification that plays critical roles in RNA regulation and cellular function. Global m6A...
Read More »scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
RMBase – decoding the atlas of RNA modifications from epitranscriptome sequencing data
Over 100 types of chemical modifications have been identified in protein-coding and noncoding RNAs (ncRNAs). However, the prevalence, regulation, and function of diverse RNA modifications remain largely unknown. Researchers from the South China University of Technology describe how to annotate, visualize, ...
Read More »The Challenges of Studying RNA Modifications with RNA Sequencing
In 2004, oncologist Gideon Rechavi at Tel Aviv University in Israel and his colleagues compared all the human genomic DNA sequences then available with their corresponding messenger RNAs — the molecules that carry the information needed to make a protein ...
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