Initiatives such as The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) have generated high-quality, multi-platform molecular data from thousands of frozen tumor...
Read More »Gene Expression, Single Nucleotide Variant and Fusion Transcript Discovery in Archival Material
Advantages of RNA-Seq over array based platforms are quantitative gene expression and discovery of expressed single nucleotide variants (eSNVs) and fusion transcripts from a single platform, but the sensitivity for each of these characteristics is unknown. Researchers at the Mayo Clinic ...
Read More »Nanostring claims: “RNA-Seq is not well suited for diagnostic use”
Earlier this week we learned that Nanostring Technologies of Seattle would be launching a $55M follow-on offering to its IPO last summer. The company said net proceeds will go toward further commercialization of NanoString’s Prosigna Breast Cancer Prognostic Gene Signature ...
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