Many of the non-coding RNAs (ncRNAs) produced by eukaryotic cells have been demonstrated to have crucial roles in biological processes. ncRNAs do not have the potential to be translated into proteins. They actively participate in the regulation, transcription, or post-transcriptional ...
Read More »Choose the right RNA-seq for your research
Next-generation sequencing (NGS) is the modern, second revolution and the spearhead of an ever-accelerating field. The NGS technology performs innovative research in a variety of different areas, such as BioPharm, Population genetics/genomics, Agriculture, Forensics, Water testing, Complex and Infectious disease ...
Read More »Non-coding RNA, splicing regulators and RNA promoters: an insight into the molecular basis of colorectal cancer
Colorectal cancer (CRC) is considered as a significant cause of death among cancer-related mortality rates [1]. The guidelines promoted by different medical associations keep pushing and promoting effective screening programs, which have increased the early diagnosis of CRC and vastly ...
Read More »Post-doc Position Available – Bioinformatics / Systems Cardiology
UniversitätsKlinikum Heidelberg – University Hospital Heidelberg The division of Bioinformatics and Systems Cardiology at the Klaus Tschira Institute for Integrative Computational Cardiology / Department of Internal Medicine III, seeks to fill one full-time position: Postdoc Bioinformatics / Systems Cardiology (m/f) ...
Read More »DASHR – a database of small human noncoding RNAs
Small non-coding RNAs (sncRNAs) are highly abundant RNAs, typically <100 nucleotides long, that act as key regulators of diverse cellular processes. Although thousands of sncRNA genes are known to exist in the human genome, no single database provides searchable, unified ...
Read More »REDItools – Uncovering RNA Editing Sites in Long Non-Coding RNAs
RNA editing is an important co/post-transcriptional molecular process able to modify RNAs by nucleotide insertions/deletions or substitutions. In human, the most common RNA editing event involves the deamination of adenosine (A) into inosine (I) through the adenosine deaminase acting on ...
Read More »BlockClust: efficient clustering and classification of non-coding RNAs from short read RNA-seq profiles
Non-coding RNAs (ncRNAs) play a vital role in many cellular processes such as RNA splicing, translation, gene regulation. However the vast majority of ncRNAs still have no functional annotation. One prominent approach for putative function assignment is clustering of transcripts ...
Read More »SeqAhead – COST – Bioinformatics for Non-Coding RNAs: State-of-the-art Training Workshop
Date – 30/6-3/7/2014, Location – Athens, Greece During the past few years non-coding RNAs (ncRNAs), previously thought as transcriptional junk, have become a research goldmine. microRNAs, long non-coding RNAs and the other ncRNA sub-classes are implicated in practically all pathophysiological ...
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