Tag Archives: neuron

Legs and arms perform very different functions. Our legs are responsible primarily for repetitive locomotion, like walking and running. Our arms and hands, by contrast, must be able to execute...

MAPseq uses RNA sequencing to rapidly and inexpensively find the diverse destinations of thousands of neurons in a single experiment in a single animal Neuroscientists have published in Neuron the details of a revolutionary new way of mapping the brain ...

Direct lineage reprogramming represents a remarkable conversion of cellular and transcriptome states. However, the intermediate stages through which individual cells progress during reprogramming are largely undefined. Here researchers from Stanford University use single-cell RNA sequencing at multiple time points to ...

A protocol is described for sequencing the transcriptome of a cell nucleus. Nuclei are isolated from specimens and sorted by FACS, cDNA libraries are constructed and RNA-seq is performed, followed by data analysis. Some steps follow published methods (Smart-seq2 for ...

The sense of smell allows chemicals to be perceived as diverse scents. Researchers at the Fred Hutchinson Cancer Research Center used single neuron RNA-Sequencing (RNA-Seq) to explore developmental mechanisms that shape this ability as nasal olfactory neurons mature in mice. ...