Population scale sweeps of viral pathogens, such as SARS-CoV-2, that incorporate large numbers of asymptomatic or mild symptom patients present unique challenges for public health agencies trying to manage both travel and local spread. Physical...
Read More »Dolomite Bio releases new application on plant protoplast RNA sequencing of leaves
Dolomite Bio, a leading provider of high throughput single cell technology, launches a new application note demonstrating single cell RNA Sequencing of plant leaf protoplasts on the Nadia Innovate The Nadia Instrument exhibits unprecedented sample type and size compatibility, allowing ...
Read More »RNA-Seq Data Analysis Workshop in Leipzig, Germany (21 – 24 September 2020)
RNA-Seq Data Analysis Workshop Quality Control, Read Mapping, Visualization and Downstream Analyses Advance your research. Understand RNA-Seq analyses challenges and solve them yourself. In a nutshell Learn the essential computing skills for NGS bioinformatics Understand NGS analysis algorithms (e.g. read alignment) and ...
Read More »Twist Bioscience expands offering of synthetic SARS-CoV-2 RNA controls for NGS diagnostics
Twist announced the addition of four new synthetic SARS-CoV-2 RNA Controls for the development, verification, and ongoing validation of diagnostic tests. The controls include new variants of SARS-CoV-2, the virus that causes COVID-19...
Read More »Hackensack University Medical Center to establish NGS laboratory for DNA / RNA profiling of cancers
John Theurer Cancer Center (JTCC), at Hackensack Meridian Health Hackensack University Medical Center in New Jersey, and Genomic Testing Cooperative (GTC), Irvine, CA, announced today an agreement to establish a state-of-the-art, next...
Read More »4th Berlin Summer School in NGS Data Analysis
When: June 15-19,2020 Where: Berlin, Germany Learn the essential computing skills for NGS bioinformatics Understand NGS analysis algorithms (e.g. read alignment) and data formats Use bioinformatics tools for handling NGS data Perform first downstream analyses for studying genetic variation Compare different approaches for differential expression ...
Read More »SparK: Publication-Quality NGS plotting tool
While there are sophisticated resources available for displaying NGS data, including the Integrative Genomics Viewer (IGV) and the UCSC genome browser, exporting regions and assembling figures for publication remains challenging. In particular, customizing track appearance and overlaying track replicates is ...
Read More »A benchmarking of pipelines for detecting ncRNAs from RNA-Seq data
Next-Generation Sequencing (NGS) is a high-throughput technology widely applied to genome sequencing and transcriptome profiling. RNA-Seq uses NGS to reveal RNA identities and quantities in a given sample. However, it produces a huge amount...
Read More »Accurate adapter information is crucial for reproducibility and reusability in small RNA-Seq studies
A necessary pre-processing data analysis step is the removal of adapter sequences from the raw reads. While most adapter trimming tools require adapter sequence as an essential input, adapter information is often incomplete or missing. This can impact quantification of ...
Read More »Ribo-depletion in RNA-Seq – Which ribosomal RNA depletion method works best?
Summary: This blogpost is focussed on ribosomal RNA (rRNA) depletion methods frequently applied to improve and economize RNA-Seq experiments. The Rise of RNA-Seq RNA-Seq Overtakes Microarrays The use of Next-Generation RNA Sequencing (RNA-Seq) has recently overtaken that of DNA-based microarrays to ...
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