Cell Microsystems, a provider of innovative tools and scalable solutions for the sorting and isolation of single cells, announced today it has been awarded a $1.5 million grant under the National Institutes of Health (NIH) SBIR program. The proposed system ...
Read More »RNA-Seq and Socioeconomics
The correlation between low socioeconomic status (SES) and poor health outcome or higher risk of disease has been consistently reported by many epidemiological studies across various race/ancestry groups. However, the biological mechanisms...
Read More »SeqLL Awarded SBIR to Advance the Development of Direct RNA Sequencing (DRS™) Technology
SeqLL, LLC announced today that it has been awarded a Phase I SBIR grant in the amount of $223,465 by the NIH/National Human Genome Research Institute to advance the development of Direct RNA Sequencing (DRS™) technology on SeqLL’s True Single ...
Read More »Power analysis at the isoform level
RNA-Sequencing (RNA-Seq) has become a routine technology for investigating gene expression differences in comparative transcriptomic studies. Differential expression (DE) analysis of the isoforms of genes is just emerging now that expression (read counts) can be estimated with higher accuracy at ...
Read More »NIH commits millions to advance RNA sequencing technology
“Parts of the genome remain hidden, or are extremely hard to analyze with current methods,” said Jeffery Schloss, Ph.D., director of the Division of Genome Sciences at the National Human Genome Research Institute (NHGRI). “If we can’t see what’s there ...
Read More »NIH to fund development of methods for direct RNA sequencing
Purpose This Funding Opportunity Announcement (FOA) solicits R01 grant applications to develop novel technologies that will enable at least one order of magnitude improvement in DNA sequencing, and practical methods for direct RNA sequencing. Advances in genomics and more broadly ...
Read More »QoRTs – a comprehensive toolset for quality control and data processing of RNA-Seq experiments
High-throughput next-generation RNA sequencing has matured into a viable and powerful method for detecting variations in transcript expression and regulation. Proactive quality control is of critical importance as unanticipated biases, artifacts, or errors can potentially drive false associations and lead ...
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