Tag Archives: noise

In this webinar, researchers from NuGEN describe a novel method for targeted depletion of unwanted transcripts in RNA-Seq libraries. The proprietary Insert Dependent Adaptor Cleavage (InDA-C) technology employs customized probes to target specific transcript species for exclusion in the final ...

Repeated cross-sectional time series single cell data confound several sources of variation, with contributions from measurement noise, stochastic cell-to-cell variation and cell progression at different rates. Time series from single cell assays are particularly susceptible to confounding as the measurements ...

RNA-seq is being used increasingly for gene expression studies and it is revolutionizing the fields of genomics and transcriptomics. However, the field of RNA-seq analysis is still evolving. Now, researchers at the University of Tennessee, Knoxville specifically designed a study ...

Various methods had been introduced for normalization and comparison of RNA-seq count data. However, they lacked objectivity because they based on ad hoc assumptions that were never verified their appropriateness. Here, researchers from Akita Prefectural University introduced a method that assumes ...

Broadcast Date: Wednesday, June 8, 2016 Time: 11:00 am ET, 8:00 am PT REGISTRATION IS FREE The cost effectiveness of RNA-Seq is often compromised by uninformative reads that are present in high abundance—a frequent consequence of standard RNA-Seq library preparation ...

Single-cell RNA-sequencing (scRNA-seq) facilitates identification of new cell types and gene regulatory networks as well as dissection of the kinetics of gene expression and patterns of allele-specific expression. However, to facilitate such analyses, separating biological variability from the high level ...