Tag Archives: non-coding RNAs

Parkinson’s disease is the second most common neurodegenerative disease in the world, yet little is known about its causes and progression...

Alignment-free RNA quantification tools have significantly increased the speed of RNA-seq analysis. However, it is unclear whether these state-of-the-art RNA-seq analysis pipelines can quantify...

Recently, identification and functional studies of circular RNAs, a type of non-coding RNAs arising from a ligation of 3′ and 5′ ends of a linear RNA molecule, were conducted in mammalian cells with the development of RNA-seq technology. Compared with ...

The analysis of small RNA NGS data together with the discovery of new small RNAs is among the foremost challenges in life science. For the analysis of raw high-throughput sequencing data Saarland University researchers implemented the fast, accurate and comprehensive ...

Added on: 15/09/2016 – Expires on: 15/10/2016 We are seeking a postdoctoral candidate to join the “microRNAs and non-coding RNAs in development and disease” team led by Dr. Francesco Nicassio. The Center for Genomic Science of IIT@SEMM (https://www.iit.it/it/centri/cgs-semm), located in ...

Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs that guide the post-transcriptional processing of other non-coding RNAs (mostly ribosomal RNAs), but have also been implicated in processes ranging from microRNA-dependent gene silencing to alternative splicing. In order to ...

Whole-transcriptome sequencing studies from recent years revealed an unexpected complexity in transcriptomes of bacteria and archaea, including abundant non-coding RNAs, cis-antisense transcription and regulatory untranslated regions (UTRs). Understanding the functional relevance of the plethora of non-coding RNAs in a given ...

A plethora of non-coding RNAs has been discovered using high-resolution transcriptomics tools, indicating that transcriptional and post-transcriptional regulation is much more complex than previously appreciated. Small RNAs associated with transcription start sites of annotated coding regions (TSSaRNAs) are pervasive in ...

Non-coding RNAs (ncRNAs) play a vital role in many cellular processes such as RNA splicing, translation, gene regulation. However the vast majority of ncRNAs still have no functional annotation. One prominent approach for putative function assignment is clustering of transcripts ...