Novel immunostimulatory dsRNAs activate antiviral responses against multiple pandemic viruses in mouse and human organ chip models. RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many ...
Read More »Research coalition compiles 100,000 sequenced genomes of COVID
A massive effort to track the COVID-19 pandemic in Arizona over the past two years resulted in the genomic sequencing of more than 100,000 samples.
Read More »What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?
Sequencing more than 170,000 single cells from animal models have provided exceptionally detailed insight into the early immune response to SARS...
Read More »Direct RNA sequencing reveals SARS-CoV-2 m6A sites
The causative agent of COVID-19 pandemic, SARS-CoV-2, has a 29,903 bases positive-sense single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential for proper function.
Read More »scRNA-Seq can define host and viral transcriptional activity at the site of infection
Influenza A virus (IAV) and SARS-CoV-2 are pandemic viruses causing millions of deaths, yet their clinical manifestations are distinctly different...
Read More »Viral sequencing can reveal how SARS-CoV-2 spreads and evolves
The emergence of SARS-CoV-2 virus variants that are adding twists in the battle against COVID-19 highlight the need for better genomic monitoring of the virus, says Katia Koelle, associate professor of biology at Emory University. “Improved genomic surveillance of SARS-CoV-2 across ...
Read More »New York, Wisconsin teams use RNA sequencing to search for molecular clues to defeat COVID-19
In the center of the COVID-19 pandemic, hospitals are racing to maintain quality care for patients with severe disease while facing a shortage of resources and limited understanding of the novel coronavirus...
Read More »Direct RNA sequencing and early evolution of SARS-CoV-2
Fundamental aspects of SARS-CoV-2 biology remain to be described, having the potential to provide insight to the response effort for this high-priority pathogen. University of Melbourne researchers...
Read More »nference® launches first-in-class single cell RNA-sequencing resource to arm researchers fighting COVID-19 pandemic
– Developed in collaboration with Janssen, the Single Cell resource is being made available on the nferX® platform for free to academic researchers worldwide – – Announcement follows nference joining the COVID-19 Healthcare Coalition, a private sector collaborative with Mayo ...
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