Researchers combine in vivo labeling, patch clamp, and single cell RNA-seq to correlate anatomy and function with gene expression in individual neurons

December 20, 2017 Leave a comment 4,975 Views

The classification of neurons into distinct types is an ongoing effort aimed at revealing and understanding the diversity of the components of the nervous system.

Patch-Seq – combines patch-clamp recording with single-cell RNA sequencing

December 22, 2015 Leave a comment 7,061 Views

Despite its importance, scientists still do not understand all of the different cell types that make up the brain. A group of researchers from Baylor College of Medicine (Drs. Andreas and Kimberley Tolias’ laboratories), the Karolinska Institutet (Dr. Rickard Sandberg’s ...

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Tag Archives: patch-clamp

Researchers combine in vivo labeling, patch clamp, and single cell RNA-seq to correlate anatomy and function with gene expression in individual neurons

Patch-Seq – combines patch-clamp recording with single-cell RNA sequencing

Establishment of a hybridoma sequencing pipeline for sequencing of antibody variable regions

RNA-seq identifies stochastic RNA editing of synaptic genes in single neurons

NVIGEN pioneers breakthrough in high-resolution tissue RNA sequencing with magnetic nanoparticle capture

RNA folding studies by tRNA structure-seq inside peptide-rich droplets reveal roles of modified nucleosides at the origin of life

GiRAFR – gRNA detection and annotation in single-cell CRISPR screens

RNA sequencing reaveals novel intracellular signaling mechanisms that promote melanoma growth

AAV-Perturb-seq – adeno-associated virus (AAV)-mediated direct in vivo single-cell CRISPR screening