The advances in high-throughput sequencing technologies are allowing more and more de novo assembling of transcriptomes from many new organisms. Some degree of automation and evaluation is...
Read More »How not to perform a differential expression analysis (or science)
By Lior Pachter – One of the maxims of computational biology is that “no two programs ever give the same result.” This is perhaps not so surprising; after all, most journals seek papers that report a significant improvement to an existing method. ...
Read More »Fighting veterinary drug abuse with RNA-Seq
Worldwide growth and performance-enhancing substances are used in cattle husbandry to increase productivity. In certain countries however e.g., in the EU, these practices are forbidden to prevent the consumers from potential health risks of substance residues in food. To maximize ...
Read More »A comparison between PCA and hierarchical clustering
Advice from Charlotte Soneson, Qlucore Introduction Graphical representations of high-dimensional data sets are at the backbone of straightforward exploratory analysis and hypothesis generation. Within the life sciences, two of the most commonly used methods for this purpose are heatmaps combined ...
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