Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data

September 8, 2014 Comments Off on Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data 4,605 Views

Allele-specific expression (ASE) studies have wide-ranging implications for genome biology and medicine. Whole transcriptome RNA sequencing (RNA-Seq) has emerged as a genome-wide tool for identifying ASE, but suffers from mapping bias favoring reference alleles. Two categories of methods are adopted ...

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Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data

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