Dear rna-seqblog community, we are excited to share with you that our article “A Detailed Catalogue of Multi-Omics Methodologies for Identification of Putative Biomarkers and Causal Molecular Networks in Translational Cancer Research” has been published in IJMS as part of ...
Read More »Single-cell RNA-seq could play a key role in personalized medicine
Researchers at MIT and Linköping University discuss the potential of single-cell RNA sequencing (scRNA-seq) to empower clinical implementation of personalized medicine. On the basis of work to date, they emphasize applications in cancer. Nevertheless, the underlying problems and solutions should be ...
Read More »Machine learning reveals correlations of gene expression in RNA-Seq data
Shirley Pepke – The complexity of cancer has famously eluded conquering by modern medicine. Every tumor has many aberrations that drive its growth. As a result, treatments that target single vulnerabilities are typically of short-lived efficacy. After being diagnosed with ...
Read More »Is Personalized Medicine Here?
Clinical application of next-generation sequencing The widespread availability of genomic analysis of tumors in clinical practice has been primarily driven by the advent of next-generation sequencing (NGS). The term “NGS” includes several types of genomic sequencing methodologies, such as targeted ...
Read More »Michael Snyder to speak about personalized medicine through the science of genomics at Museum of the Rockies
Michael Snyder, Ascherman Professor, chair of the Department of Genetics and director of the Center of Genomics and Personalized Medicine at Stanford University, will present “Personalized Medicine: New Directions to Revolutionize Management of Health and Disease,” on Thursday, Feb. 25. ...
Read More »RNA-Seq and SCA Could Have a Huge Impact on Personalized Medicine
Analysis of the RNA-Seq and SCA Publication Landscape from Genetic Engineering News by Enal Razvi, Ph.D. and Gary Oosta, Ph.D. Select Biosciences performed an analysis on the RNA-Seq space—one of the exciting segments of the broader next-generation sequencing (NGS) space ...
Read More »The statistical universe is a single patient – pathway analysis from “N-of-1” RNA-Seq data
The emergence of precision medicine allowed the incorporation of individual molecular data into patient care. Indeed, DNA sequencing predicts somatic mutations in individual patients. However, these genetic features overlook dynamic epigenetic and phenotypic response to therapy. Meanwhile, accurate personal transcriptome ...
Read More »NCI, TGEN and Dell collaborate on RNA-Seq Database
PHOENIX, Ariz. – Sept. 10, 2014 – Dell, Terascala and the Translational Genomics Research Institute (TGen) are installing state-of-the-art computing and programing specialized for human genome investigations at the National Cancer Institute (NCI). As part of a formal collaboration, Dell ...
Read More »Next Generation Sequencing (NGS) Market – Global Forecast to 2020
Next Generation Sequencing (NGS) Market by Platforms (Illumina HiSeq, MiSeq, HiSeqX Ten, NextSeq 500,Thermo Fisher Ion Proton/PGM), Bioinformatics (Exome Sequencing, RNA-Seq, ChIP-Seq), Technology (SBS, SMRT) & by Application (Diagnostics, Personalized Medicine) – Global Forecast to 2020 The next generation sequencing ...
Read More »RNA sequence could help doctors to tailor unique prostate cancer treatment programs
from Medical Xpress Sequencing RNA, not just DNA, could help doctors predict how prostate cancer tumors will respond to treatment, according to research published in the open access journal Genome Biology. Because a tumor’s RNA shows the real time changes ...
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