Tag Archives: pipeline

Choosing a next-generation sequencing pipeline

rna-seq

The next-generation sequencing (NGS) technologies are revolutionary tools which have made possible achieving remarkable advances in genetics since the beginning of the twenty-first century. Thanks to the possibility to produce large amount of sequence data, these tools are going to ...

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Industry Press from ASHG Day 1

rna-seq

10:00 ET New England Biolabs® and Directed Genomics Partner to Develop Novel Target Enrichment Technologies for Next Generation Sequencing  New England Biolabs (NEB®) and Directed Genomics together announce that they have established a partnership to develop a suite of new ...

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Meet the Winner of Appistry’s Pipeline Challenge

Today Appistry announced the winner of its inaugural Pipeline Challenge. The winner is a project team led by Dr. Benjamin Darbro, director of the Shivanand R. Patil Cytogenetics and Molecular Laboratory at the University of Iowa Hospital and Clinics. Dr. Darbro won ...

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Challenges and strategies for RNA-Seq data analysis

rna-seq

RNA-seq is a methodology for RNA profiling based on next-generation sequencing that enables to measure and compare gene expression patterns at unprecedented resolution. Although the appealing features of this technique have promoted its application to a wide panel of transcriptomics ...

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SUPPA – a super-fast pipeline for alternative splicing analysis from RNA-Seq

rna-seq

High-throughput RNA sequencing allows genome-wide analyses of pre-mRNA splicing across multiple conditions. However, the increasing number of available datasets represents a major challenge in terms of time and storage required for analyses. Now, a team led by researchers at the ...

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Pegasus – a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer

rna-seq

The extraordinary success of imatinib in the treatment of BCR-ABL1 associated cancers underscores the need to identify novel functional gene fusions in cancer. RNA sequencing offers a genome-wide view of expressed transcripts, uncovering biologically functional gene fusions. Although several bioinformatics ...

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Cofactor Genomics Awarded NIH Grant to Develop a Circular RNA Enrichment Kit and Reference Profile

rna-seq

August 2014, Cofactor Genomics has been awarded a grant by the National Institute of Mental Health (NIMH), an institute of the NIH, to develop a standardized enrichment kit and define the normal reference profile for circular RNAs (circRNA) in the nervous ...

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READemption – A tool for the computational analysis of deep-sequencing-based transcriptome data

rna-seq

RNA-Seq has become a potent and widely used method to qualitatively and quantitatively study transcriptomes. In order to draw biological conclusions based on RNA-Seq data, several steps some of which are computationally intensive, have to be taken. Researchers at the ...

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