April 20, 2017 1:00 p.m. CDT Presented by: Victor Martinez, Ph.D. Biomedical Sciences British Columbia Cancer Research Centre PIWI-interacting RNAs (piRNAs) are small (24-32bp) non-coding RNAs with a key role in epigenetic regulation of gene expression and ...
Read More »iSmaRT – a toolkit for a comprehensive analysis of small RNA-Seq data
The interest in investigating the biological roles of small non-coding RNAs (sncRNAs) is increasing, due to the pleiotropic effects of these molecules exert in many biological contexts. While several methods and tools are available to study microRNAs (miRNAs), only few ...
Read More »DASHR – a database of small human noncoding RNAs
Small non-coding RNAs (sncRNAs) are highly abundant RNAs, typically <100 nucleotides long, that act as key regulators of diverse cellular processes. Although thousands of sncRNA genes are known to exist in the human genome, no single database provides searchable, unified ...
Read More »Tailor – a computational framework for detecting non-templated tailing of small silencing RNAs
Small silencing RNAs, including microRNAs, endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), have been shown to play important roles in fine-tuning gene expression, defending virus and controlling transposons. Loss of small silencing RNAs or components in their pathways ...
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