Tag Archives: preprocessing

RNA sequencing (RNA-seq) has become the standard means of analyzing gene and transcript expression in high-throughput. While previously sequence alignment was a time demanding step...

Systematic measurement biases make normalization an essential step in single-cell RNA sequencing (scRNA-seq) analysis. There may be multiple competing considerations behind the assessment of normalization performance, of which some may be study specific. Researchers at UC Berkeley have developed “scone”- ...

The Cancer Genome Atlas (TCGA) RNA-Sequencing data are used widely for research. TCGA provides “Le3” data, which have been processed using a pipeline specific to that resource. However, researchers from the University of Utah have found using experimentally derived data ...