Tag Archives: protein-coding genes

Long non-coding RNAs (lncRNAs) constitute a large, yet mostly uncharacterized fraction of the mammalian transcriptome. Such characterization requires a comprehensive, high-quality annotation of their gene structure and boundaries, which is currently lacking. Here researchers from the Barcelona Institute of Science ...

Transcriptomics is an important approach that has helped researchers understand the molecular basis of disease in a range of species. Whilst for many years microarrays were the tool of choice, RNA-Seq has now emerged as the standard method for analysing ...

Pervasive transcription of the human genome generates RNAs whose mode of formation and functions are largely uncharacterized. Now researchers from Yale University School of Medicine have discovered yet another type of RNA: DoGs, which stands for – downstream of gene containing ...

Penn Medicine study has implications for 100 top-selling US drugs, half of which target daily-oscillating genes PHILADELPHIA — A new effort mapping 24-hr patterns of expression for thousands of genes in 12 different mouse organs – five years in the making ...

Analysis of differential gene expression by RNA sequencing (RNA-Seq) is frequently done using feature counts, i.e. the number of reads mapping to a gene. However, commonly used count algorithms (e.g. HTSeq) do not address the problem of reads aligning with ...

Insects are one of the largest classes of animals on Earth and constitute more than half of all living species. The i5k initiative has begun sequencing of more than 5,000 insect genomes, which should greatly help in exploring insect resource ...