Researchers at Oregon State University have used deep learning to decipher which ribonucleic acids have the potential to encode proteins. The gated recurrent neural network developed in the College...
Read More »IsoFunc – Functional Annotation of Human Protein-Coding Splice Variant Using Multiple Instance Learning
The vast majority of human multiexon genes undergo alternative splicing and produce a variety of splice variant transcripts and proteins, which can perform different functions. These protein-coding splice variants (PCSVs) greatly increase the functional diversity of proteins. Most functional annotation ...
Read More »Researchers estimate number of human transcripts with protein-coding potential is greater than 200,000
Biological and biomedical research relies on comprehensive understanding of protein-coding transcripts. However, the total number of human proteins is still unknown due to the prevalence of alternative splicing. Now, a team led by researchers at Shanghai Jiao Tong University have ...
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