Tag Archives: proteomics

WIlsON: Web-based Interactive Omics VisualizatioN

High throughput (HT) screens in the omics field are typically analyzed by automated pipelines that generate static visualizations and comprehensive spreadsheet data for scientists. However, exploratory and hypothesis driven data analysis are key aspects for the understanding of biological systems, ...

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Utilizing RNA-Seq data to improve proteomics

rna-seq

Shotgun proteomics utilizes a database search strategy to compare detected mass spectra to a library of theoretical spectra derived from reference genome information. As such, the robustness of proteomics results is contingent upon the completeness and accuracy of the gene ...

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Alternative transcriptome assembly tools improve proteomics informed by transcriptomics (PIT) workflow

rna-seq

RNA sequencing is a powerful method to build reference transcriptome assemblies and eventually sample-specific protein databases for mass spectrometry-based analyses. This novel proteomics informed by transcriptomics (PIT) workflow improves sample-specific proteome characterization of dynamic- and especially non-model organism proteomes, and ...

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Proteomics Informed by Transcriptomics

rna-seq

With the recent advent of RNA-seq technology the proteomics community has begun to generate sample-specific protein databases for peptide and protein identification, an approach we call proteomics informed by transcriptomics (PIT). This approach has gained a lot of interest, particularly ...

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