RNA-Sequencing has been the leading technology to quantify expression of thousands genes simultaneously. The data analysis of an RNA-Seq experiment starts from aligning short reads to the reference genome/transcriptome or reconstructed transcriptome. However, current aligners lack the sensitivity to distinguish ...
Read More »The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes
Although individual pseudogenes have been implicated in tumour biology, the biomedical significance and clinical relevance of pseudogene expression have not been assessed in a systematic way. Here researchers from the University of Texas MD Anderson Cancer Center generate pseudogene expression ...
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