switchde – Inference of switch-like differential expression along single-cell pseudotemporal trajectories

December 30, 2016 Leave a comment 7,194 Views

Pseudotime analyses of single-cell RNA-seq data have become increasingly common. Typically, a latent trajectory corresponding to a biological process of interest – such as differentiation or cell cycle – is discovered. However, relatively little attention has been paid to modelling ...

A new statistical method allows researchers to infer different developmental processes from RNA-Seq data

September 6, 2016 Leave a comment 11,157 Views

Through RNA sequencing, researchers can measure which genes are expressed in each individual cell of a sample. A new statistical method allows researchers to infer different developmental processes from a cell mixture consisting of asynchronous stages. This finding has been ...

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Tag Archives: pseudotime

switchde – Inference of switch-like differential expression along single-cell pseudotemporal trajectories

A new statistical method allows researchers to infer different developmental processes from RNA-Seq data

Novel guidelines help select optimal deconvolution method

An RNA-Seq framework for profiling target selectivity and physiological effects of antisense peptide nucleic acids (PNAs)

Single cell sequencing unravels molecular identity of rare renal cell types

SMIXnorm – fast and accurate RNA-Seq data normalization for FFPE Samples

TEA-seq – simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility

First use of both bulk and single-cell RNA sequencing of human bladder tumors to study resistance to immunotherapy

Post-doc position available – transcriptome bioinformatics and RNA sequencing