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Tag Archives: Pseudouridine site

PseUI – Pseudouridine sites identification based on RNA sequence information

October 12, 2018 Leave a comment 1,152 Views

rna-seq

Pseudouridylation is the most prevalent type of posttranscriptional modification in various stable RNAs of all organisms, which significantly affects many cellular processes that are regulated by RNA. Thus, accurate identification of pseudouridine (Ψ)...

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TET1 promotes RXRα expression and adipogenesis through DNA demethylation
8 March 2021
c-CSN: Single-cell RNA Sequencing Data Analysis by Conditional Cell-specific Network
8 March 2021
Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits
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B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers
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Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones
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Therapeutic implications of <em>C. albicans-S. aureus</em> mixed biofilm in a murine subcutaneous catheter model of polymicrobial infection
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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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