Malignant tumors of the central nervous system (CNS) cause substantial morbidity and mortality, yet efforts to optimize chemo- and radiotherapy have largely failed to improve dismal prognoses. Over the past decade, RNA sequencing (RNA-seq) has emerged as a powerful tool ...
Read More »RNA-Seq Identifies a Panel of MicroRNAs as Diagnostic Biomarkers for Prostate Cancer
Prostate cancer is the most common non-cutaneous cancer among men; yet, current diagnostic methods are insufficient, and more reliable diagnostic markers need to be developed. One answer that can bridge this gap may lie in microRNAs. These small RNA molecules ...
Read More »Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing
The majority of the human genome is differentially expressed across a wide dynamic range to produce a spectrum of protein-coding and noncoding RNAs, generating a transcriptome of unexpected scale and complexity. These features present a challenge for gene-expression profiling with ...
Read More »Study suggests that microarrays can perform on nearly equal footing with RNA-Seq
The arrival of RNA-seq as a high-throughput method competitive to the established microarray technologies has necessarily driven a need for comparative evaluation. To date, cross-platform comparisons of these technologies have been relatively few in number of platforms analyzed and were ...
Read More »Astroid – transcriptome reconstruction on the basis of a flow network
The advancement of RNA sequencing (RNA-seq) has provided an unprecedented opportunity to assess both the diversity and quantity of transcript isoforms in an mRNA transcriptome. In this paper, researchers from the University of Kentucky revisit the computational problem of transcript ...
Read More »Genomics Market worth $19.0 Billion by 2018
DALLAS, January 27, 2014 /PRNewswire/ — New analysis from MarketsandMarkets “Genomics Market by Products – [Instruments (NGS platform, Microarray, RT-PCR), Consumables (Genechips, Reagents for DNA Extraction & Purification, Sequencing)], Services (Sequencing & Microarray Services, and Software) – Global Forecast to 2018“, ...
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