Isoform prefiltering improves performance of count-based methods for analysis of differential transcript usage

February 2, 2016 Leave a comment 3,776 Views

RNA-seq has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development of new treatments or ...

Differential transcript usage from RNA-seq data – isoform pre-filtering improves performance of count-based methods

August 27, 2015 Leave a comment 6,937 Views

Large-scale sequencing of cDNA (RNA-seq) has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development ...

RNA-Seq Blog Transcriptome Research & Industry News

Tag Archives: quantitative analysis

Isoform prefiltering improves performance of count-based methods for analysis of differential transcript usage

Differential transcript usage from RNA-seq data – isoform pre-filtering improves performance of count-based methods

Establishment of a hybridoma sequencing pipeline for sequencing of antibody variable regions

RNA-seq identifies stochastic RNA editing of synaptic genes in single neurons

NVIGEN pioneers breakthrough in high-resolution tissue RNA sequencing with magnetic nanoparticle capture

RNA folding studies by tRNA structure-seq inside peptide-rich droplets reveal roles of modified nucleosides at the origin of life

GiRAFR – gRNA detection and annotation in single-cell CRISPR screens

RNA sequencing reaveals novel intracellular signaling mechanisms that promote melanoma growth

AAV-Perturb-seq – adeno-associated virus (AAV)-mediated direct in vivo single-cell CRISPR screening