Tag Archives: read trimming

High-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is widely but heterogeneously ...

In Nathaniel Heintz’s molecular biology lab at Rockefeller University, scientists study brain function and dysfunction under a wide array of conditions, from drug abuse to depression. Marian Mellén, a postdoctoral fellow in the lab, is using RNA-seq and other data ...

Next Generation Sequencing is having an extremely strong impact in biological and medical research and diagnostics, with applications ranging from gene expression quantification to genotyping and genome reconstruction. Sequencing data is often provided as raw reads which are processed prior ...