Tag Archives: regulatory network

Genome-wide map of regulatory interactions in the human genome

rna-seq

Increasing evidence suggests that interactions between regulatory genomic elements play an important role in regulating gene expression. Researchers at Stanford University School of Medicine generated a genome-wide interaction map of regulatory elements in human cells (ENCODE tier 1 cells, K562, ...

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iRegulon: From a Gene List to a Gene Regulatory Network

rna-seq

Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. Researchers at the KU Leuven Center for Human Genetics developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying ...

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