Tag Archives: regulatory network

Increasing evidence suggests that interactions between regulatory genomic elements play an important role in regulating gene expression. Researchers at Stanford University School of Medicine generated a genome-wide interaction map of regulatory elements in human cells (ENCODE tier 1 cells, K562, ...

Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. Researchers at the KU Leuven Center for Human Genetics developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying ...

We are witnessing rapid progress in the development of methodologies for building the combinatorial gene regulatory networks involving both TFs (Transcription Factors) and miRNAs (microRNAs). There are a few tools available to do these jobs but most of them are ...