Tag Archives: RIKEN

By combining a number of methods, researchers from the RIKEN Advanced Center for Computing and Communications (ACCC) in Japan have developed a method that allows full-length sequencing of the...

Total RNA sequencing has been used to reveal poly(A) and non-poly(A) RNA expression, RNA processing and enhancer activity. To date, no method for full-length total RNA sequencing of single cells has been developed despite the potential of this technology for ...

High-throughput single-cell RNA-seq methods assign limited unique molecular identifier (UMI) counts as gene expression values to single cells from shallow sequence reads and detect limited gene counts. Researchers from the RIKEN Institute thus developed a high-throughput single-cell RNA-seq method, Quartz-Seq2, ...

The ALS Research Forum – A new genomic resource may help researchers unravel the role of key RNA-binding proteins in ALS. The atlas, developed at the Riken Institute in Yokohama, Japan, contains 27,919 long non-coding RNAs – including 19,175 potentially ...

from Science Daily – New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia. The implicated loci contribute to schizophrenia risk by affecting alternative splicing, part of the process that translates the same DNA ...

RNA-seq enables gene expression profiling in selected spatiotemporal windows and yields massive sequence information with relatively low cost and time investment, even for non-model species. However, there remains a large room for optimizing its workflow, in order to take full ...

Using whole genomic sequencing and RNA-Seq, scientists from RIKEN in Japan have for the first time demonstrated the profound effect that chronic hepatitis infection and inflammation can have on the genetic mutations found in tumors of the liver, potentially paving ...

FANTOM, a large international consortium led by RIKEN releases today the first comprehensive map of gene activity across the human body, and provides the first holistic view of the complex networks that regulate gene expression across the wide variety of ...

ZENBU, a new, freely available bioinformatics tool developed at the RIKEN Center for Life Science Technology in Japan, enables researchers to quickly and easily integrate, visualize and compare large amounts of genomic information resulting from large-scale, next-generation sequencing experiments. Next-generation ...