Tag Archives: RNA-binding protein

Identification of high-confidence RNA regulatory elements by combinatorial classification of RNA-protein binding sites

rna-seq

Crosslinking immunoprecipitation sequencing (CLIP-seq) technologies have enabled researchers to characterize transcriptome-wide binding sites of RNA-binding protein (RBP) with high resolution. Tsinghua University researchers apply a soft-clustering method, RBPgroup, to various CLIP-seq datasets to group together RBPs that specifically bind the ...

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Identifying RBP Targets with RIP-seq

rna-seq

One of the challenges to assess the impact of RBPs on posttranscriptional gene regulation is identifying and quantifying the RNA and protein components of ribonucleoprotein complexes (RNPs) in a cellular context. The human genome is estimated to contain 1542 RBPs. ...

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