N6-methyladenosine (m6A) is an abundant RNA modification that plays critical roles in RNA regulation and cellular function. Global m6A...
Read More »RMBase – decoding the atlas of RNA modifications from epitranscriptome sequencing data
Over 100 types of chemical modifications have been identified in protein-coding and noncoding RNAs (ncRNAs). However, the prevalence, regulation, and function of diverse RNA modifications remain largely unknown. Researchers from the South China University of Technology describe how to annotate, visualize, ...
Read More »RNAEditor – easy detection of RNA editing events and the introduction of editing islands
RNA editing of adenosine residues to inosine (‘A-to-I editing’) is the most common RNA modification event detectible with RNA sequencing (RNA-seq). While not directly detectable, inosine is read by next-generation sequencers as guanine. Therefore, mapping RNA-seq reads to their corresponding ...
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