Tag Archives: RNA-Seq Data

Bringing RNA-Seq into Undergraduate Education

rna-seq

Virtual Workshop, June 2016 Cold Spring Harbor Laboratory’s DNA Learning Center (DNALC) invites you to apply to participate in a free 2-week online workshop for our NSF funded project, Infrastructure and Training to Bring Next-generation Sequence (NGS) Analysis Into Undergraduate ...

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Predicting Protein Functions at the Isoform Level

rna-seq

Integrate isoform co-expression networks for protein isoform function prediction. Propose a novel hybrid method of multiple-instance and semi-supervised graph learning. Predict isoform-isoform interactions and discover isoform functional modules. Over the past few decades, many computational methods have been developed to ...

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A Comparison of Next Generation Sequencing Technologies for Transcriptome Assembly

De novo assembled transcriptomes, in combination with RNA-Seq, are powerful tools to explore gene sequence and expression level in organisms without reference genomes. Investigators must first choose which high throughput sequencing platforms will provide data most suitable for their experimental ...

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IUTA – a tool for effectively detecting differential isoform usage from RNA-Seq data

rna-seq

Most genes in mammals generate several transcript isoforms that differ in stability and translational efficiency through alternative splicing. Such alternative splicing can be tissue- and developmental stage-specific, and such specificity is sometimes associated with disease. Thus, detecting differential isoform usage ...

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SAT-Assembler – A Scalable and Accurate Targeted Gene Assembly Tool for Next-Generation Sequencing Data

Gene assembly, which recovers gene segments from short reads, is an important step in functional analysis of next-generation sequencing data. Lacking quality reference genomes, de novo assembly is commonly used for RNA-Seq data of non-model organisms and metagenomic data. However, ...

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