Tag Archives: rna structure

A key aspect of RNA secondary structure prediction is the identification of novel functional elements. This is a challenging task because these elements typically are embedded in longer transcripts where the borders between the element and flanking regions have to ...

Transcriptome-wide RNA structure probing coupled with NGS yields the RNA structurome. RNA structurome data tremendously improve prediction of in vivo RNA structure. RNA structurome data uncover relationships between RNA structure and gene regulation. RNA folds into intricate structures that enable ...

Temperature is one of the decisive signals that a mammalian pathogen has entered its warm-blooded host. Among the many ways to register temperature changes, bacteria often use temperature-modulated structures in the untranslated region of mRNAs. In this article, the authors ...

by Xiaole Shirley Liu RNA-seq Experiments Analysis: read mapping, expression index, isoform inference, differential expression RNA structure prediction Covariance model Base-pair maximization Free energy method