Tag Archives: RNA synthesis

Modeling RNA dynamics without metabolic labeling

Transcript’s abundance is typically considered a proxy of the corresponding genes transcriptional activity. Yet, a poorly transcribed gene could see many of its RNA molecules accumulate just because they are highly stable. Conversely, if a gene is very actively transcribed ...

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TT-seq maps the human transient transcriptome

Transcription of eukaryotic genomes produces protein-coding mRNAs and diverse noncoding RNAs (ncRNAs), including enhancer RNAs (eRNAs). Most ncRNAs are rapidly degraded, difficult to detect, and thus far have not been mappable in their full range. Mapping of transient RNAs is ...

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