For the first time, scientists at the Federal University of São Paulo (UNIFESP) in Brazil have shown that infection by SARS-CoV-2, the virus that causes COVID-19, changes the functioning of host cell RNA. They arrived at this conclusion by analyzing ...
Read More »New type of RNA discovered
Novel immunostimulatory dsRNAs activate antiviral responses against multiple pandemic viruses in mouse and human organ chip models. RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many ...
Read More »An application of RNA sequencing toward mRNA based nanotherapeutics against SARS-CoV-2 infections
Due to fast transmission and various circulating SARS-CoV-2 variants, a significant increase of coronavirus 2019 infection cases with acute respiratory symptoms has prompted worries about the...
Read More »Research coalition compiles 100,000 sequenced genomes of COVID
A massive effort to track the COVID-19 pandemic in Arizona over the past two years resulted in the genomic sequencing of more than 100,000 samples.
Read More »Certainty at a time of uncertainty: An accurate picture of circulating SARS-CoV-2 variants
Mutants, variants and vaccines: The twists and turns in the continually evolving COVID-19 pandemic Since its emergence globally in early 2020, SARS-CoV-2...
Read More »What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?
Sequencing more than 170,000 single cells from animal models have provided exceptionally detailed insight into the early immune response to SARS...
Read More »SwabSeq – Scalable, Sensitive and Fast COVID-19 Testing
The UCLA–developed diagnostic technology has helped keep the university and other large client organizations operational during the pandemic. After much of Los Angeles went dark in the spring of 2020
Read More »Point-of-care platform for rapid multiplexed detection of SARS-CoV-2 variants and respiratory pathogens
The rise of highly transmissible SARS-CoV-2 variants brings new challenges and concerns with vaccine efficacy, diagnostic sensitivity, and public health responses to end the pandemic. Widespread detection of variants is critical to inform policy decisions to mitigate further spread, and postpandemic ...
Read More »RNA-Seq data pipeline quickly identifies SARS-CoV-2 therapeutics
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a novel Betacoronavirus that was first reported in Wuhan, China in Dec...
Read More »Nanopore ReCappable Sequencing (NRCeq) – a new technique that can identify capped full-length RNAs
The SARS-CoV-2 virus has a complex transcriptome characterised by multiple, nested sub genomic RNAs used to express structural and accessory proteins. Long-read sequencing technologies such as nanopore...
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