RNA-Seq Blog Transcriptome Research & Industry News
A massive effort to track the COVID-19 pandemic in Arizona over the past two years resulted in the genomic sequencing of more than 100,000 samples.
Read More »Research coalition compiles 100,000 sequenced genomes of COVID
Certainty at a time of uncertainty: An accurate picture of circulating SARS-CoV-2 variants
Mutants, variants and vaccines: The twists and turns in the continually evolving COVID-19 pandemic Since its emergence globally in early 2020, SARS-CoV-2...
Read More »What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?
Sequencing more than 170,000 single cells from animal models have provided exceptionally detailed insight into the early immune response to SARS...
Read More »SwabSeq – Scalable, Sensitive and Fast COVID-19 Testing
The UCLA–developed diagnostic technology has helped keep the university and other large client organizations operational during the pandemic. After much of Los Angeles went dark in the spring of 2020
Read More »Point-of-care platform for rapid multiplexed detection of SARS-CoV-2 variants and respiratory pathogens
The rise of highly transmissible SARS-CoV-2 variants brings new challenges and concerns with vaccine efficacy, diagnostic sensitivity, and public health responses to end the pandemic. Widespread detection of variants is critical to inform policy decisions to mitigate further spread, and postpandemic ...
Read More »RNA-Seq data pipeline quickly identifies SARS-CoV-2 therapeutics
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a novel Betacoronavirus that was first reported in Wuhan, China in Dec...
Read More »Nanopore ReCappable Sequencing (NRCeq) – a new technique that can identify capped full-length RNAs
The SARS-CoV-2 virus has a complex transcriptome characterised by multiple, nested sub genomic RNAs used to express structural and accessory proteins. Long-read sequencing technologies such as nanopore...
Read More »Analysis workflow for publicly available RNA-sequencing datasets
Differential gene expression analysis is widely used to study changes in gene expression profiles between two or more groups of samples (e.g., physiological versus pathological conditions...
Read More »Monitoring SARS-CoV-2 using wastewater-based metatranscriptomic sequencing and droplet digital PCR to characterize RNA viromes
Alternative viral detection methods have been critical in the fight against COVID-19, helping to reduce the burden on our healthcare system. In a new study...
Read More »Direct RNA sequencing reveals SARS-CoV-2 m6A sites
The causative agent of COVID-19 pandemic, SARS-CoV-2, has a 29,903 bases positive-sense single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential for proper function.
Read More »