Patterns of sequencing coverage bias revealed by ultra-deep sequencing

June 17, 2014 Leave a comment 4,959 Views

Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage. Researchers at Uppsala University, Sweden have investigated patterns of local variation in sequencing coverage by utilising ultra-deep ...

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Patterns of sequencing coverage bias revealed by ultra-deep sequencing

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