Tag Archives: Shanghai Institutes for Biological Sciences

Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data


Allele-specific expression (ASE) studies have wide-ranging implications for genome biology and medicine. Whole transcriptome RNA sequencing (RNA-Seq) has emerged as a genome-wide tool for identifying ASE, but suffers from mapping bias favoring reference alleles. Two categories of methods are adopted ...

Read More »