High-coverage single-cell RNA-sequencing identifies somatosensory neuron types

January 4, 2016 Leave a comment 4,141 Views

Sensory neurons are distinguished by distinct signaling networks and receptive characteristics. Thus, sensory neuron types can be defined by linking transcriptome-based neuron typing with the sensory phenotypes. Here researchers from the Shanghai Institutes for Biological Sciences classify somatosensory neurons of ...

Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data

September 8, 2014 Comments Off on Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data 4,350 Views

Allele-specific expression (ASE) studies have wide-ranging implications for genome biology and medicine. Whole transcriptome RNA sequencing (RNA-Seq) has emerged as a genome-wide tool for identifying ASE, but suffers from mapping bias favoring reference alleles. Two categories of methods are adopted ...

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Tag Archives: Shanghai Institutes for Biological Sciences

High-coverage single-cell RNA-sequencing identifies somatosensory neuron types

Comparison of Computational Methods for Identification of Allele-Specific Expression based on Next Generation Sequencing Data

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