Single-cell RNA sequencing (scRNA-seq) has enabled researchers to study gene expression at a cellular resolution. However, noise due to amplification and dropout may obstruct analyses, so scalable...
Read More »Single-Cell RNA Sequencing From Frozen Samples Feasible
GenomeWeb – A new study suggests the accuracy of transcriptional profiles produced from single cells does not seem to suffer significantly when samples are frozen beforehand. Researchers from Spain and Israel did RNA sequencing on nearly 700 individual cells nabbed ...
Read More »scDD – A statistical approach for identifying differential distributions in single-cell RNA-seq experiments
The ability to quantify cellular heterogeneity is a major advantage of single-cell technologies. Although understanding such heterogeneity is of primary interest in a number of studies, for convenience, statistical methods often treat cellular heterogeneity as a nuisance factor. A team ...
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