High-dimensional data, such as those generated by single-cell RNA sequencing (scRNA-seq), present challenges in interpretation and visualization. Numerical and computational methods for dimensionality reduction allow for low-dimensional representation of...
Read More »1CellBio Announces Custom Targeted Bead Program to Accelerate Next Phase in Single-Cell Analysis
1CellBio today announced a new program to supply select customers with its proprietary inDrop™ hydrogel beads synthesized with custom primers that target user-specified transcripts. “This new program enables researchers to focus their sequencing depth on their genes of interest rather ...
Read More »Single cell combinatorial indexing reveals a landscape of mammalian development
New technology enables single cell analysis of mouse embryonic development Scientists from Seattle and Berlin have published an atlas on mouse embryonic...
Read More »Mapping the Mouse Cell Atlas by Microwell-Seq
Single-cell RNA sequencing (scRNA-seq) technologies are poised to reshape the current cell-type classification system. However, a transcriptome-based single-cell atlas has not been achieved for complex mammalian systems...
Read More »A 3D printed droplet microfluidic device for single cell RNA-sequencing
New Device Enables Low-Cost Single-Cell Analysis and Leads to Identification of Fibroblast Subtypes in Rheumatoid Arthritis Patients Single-cell analysis holds enormous potential to study how individual cells influence disease and respond to treatment, but the lack of cost-effective and user-friendly ...
Read More »BD Expands Genomics Portfolio with New Single Cell Platform for RNA Expression Analysis
BD (Becton, Dickinson and Company) , a leading global medical technology company, today announced the launch of BD Rhapsody, a platform for single cell analysis with the ability to detect rare molecules responsible for biological diversity that are often missed with ...
Read More »RNA-Seq, Single Cell Analysis & Single Molecule Analysis 2017
Welcome to the Select Biosciences, Inc. NGS, RNA-Seq, Single Cell Analysis & Single Molecule Analysis: Research to Diagnostics 2017 Conference. This conference brings together technology development and applications of: RNA-Seq Single Cell Analysis (SCA) Single Molecule Analysis (SMA) It has ...
Read More »RNA-Seq methods for transcriptome analysis
Deep sequencing has been revolutionizing biology and medicine in recent years, providing single base-level precision for our understanding of nucleic acid sequences in high throughput fashion. Sequencing of RNA, or RNA-Seq, is now a common method to analyze gene expression ...
Read More »Application of single-cell RNA-seq in the design of an anticancer regimen
Intratumoral heterogeneity hampers the success of marker-based anticancer treatment because the targeted therapy may eliminate a specific subpopulation of tumor cells while leaving others unharmed. Accordingly, a rational strategy minimizing survival of the drug-resistant subpopulation is essential to achieve long-term ...
Read More »Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
It has long been the dream of biologists to map gene expression at the single-cell level. With such data one might track heterogeneous cell sub-populations, and infer regulatory relationships between genes and pathways. Recently, RNA sequencing has achieved single-cell resolution. ...
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