Sequencing more than 170,000 single cells from animal models have provided exceptionally detailed insight into the early immune response to SARS...
Read More »Smart-seq-total – a method capable of assaying a broad spectrum of both coding and noncoding RNA from a single cell
The ability to interrogate total RNA content of single cells would enable better mapping of the transcriptional logic behind emerging cell types and states. However, current single-cell RNA-sequencing...
Read More »scRNA-Seq reveals how genetic ancestry shapes immune response to influenza virus
A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain...
Read More »New method to add “Time” resolution to your single-cell RNA-seq
The understanding of individual cells has enormously improved with the application of single-cell RNA-sequencing approaches, enabling researchers to...
Read More »Using Single-Cell RNA Sequencing Analysis to Predict CAR T Cell Outcomes
RNA sequencing is a biological sample genomic technique that detects and quantitatively analyzes the messenger RNA modules. It’s useful to investigate cellular responses. Over the past few years, it has fuelled medical research and innovation. For practical purposes, samples containing ...
Read More »Long term and short-term effects of RNA fixation on Single Cell RNA Sequencing
Cell performs various functions inside a living organism, of which development of the embryo is considered most significant as it is controlled by a cyclic series of accurate behaviors exhibited by the cell. The development of the embryo is maintained ...
Read More »RNA timestamps identify the age of single molecules in RNA sequencing
Current approaches to single-cell RNA sequencing (RNA-seq) provide only limited information about the dynamics of gene expression. Researchers from MIT and the Broad Institute of Harvard and MIT present RNA timestamps, a method for inferring the age...
Read More »Single cells reveal genetic connections of neurodevelopmental disorders
A large number of genes has been implicated in neurodevelopmental disorders (NDDs) such as autism, developmental delays, intellectual disabilities and epilepsy, but it is difficult to determine how these genes, individually and as a group, contribute to...
Read More »Bioinformatician, Post-doctoral candidate in Bioinformatics
Introduction A full-time position is available within the laboratory for Molecular Neurogenetics (www.molecular-neurogenetics.lu.se) led by Johan Jakobsson. The Jakobsson lab is interested in how gene expression is regulated in the brain and how this process influence neurodegenerative diseases, psychiatric disorders and brain ...
Read More »Massively parallel and time-resolved RNA sequencing in single cells with scNT-seq
Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Researchers from the University of Pennsylvania have developed single-cell metabolically labeled new RNA tagging sequencing (scNT-seq), a method for massively parallel analysis of newly transcribed and ...
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