Long-read sequencing of the transcriptome reveals novel spliced genes that are not annotated in GENCODE and are missed by short-read RNA-Seq

July 1, 2016 Leave a comment 4,902 Views

Short-read sequencing has enabled the de novo assembly of several individual human genomes, but with inherent limitations in characterizing repeat elements. Now, an international team led by researchers at USC have sequenced a Chinese individual HX1 by single-molecule real-time (SMRT) ...

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Long-read sequencing of the transcriptome reveals novel spliced genes that are not annotated in GENCODE and are missed by short-read RNA-Seq

DCoNA – a tool for fast differential correlation network analysis

SpliceVault – predicting the precise nature of variant-associated mis-splicing

High-throughput droplet-based analysis of influenza A virus genetic reassortment by single-virus RNA sequencing

The way genes are switched on in one-cell embryos may resemble the trigger for cancer

scONE-seq – A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

Phasik – inferring cell cycle phases from a partially temporal network of protein interactions

Single-cell transcriptomic profiling of Crohn’s disease reveals a detailed picture of inflammation in the gut