Sequencing has become one of the most powerful tools in state of the art research projects. Lexogen is dedicated to the development of innovative technologies that empower next generation sequencing (NGS). As much as we care about innovations, we also ...
Read More »Upcoming Webinar – Controlling RNA-Seq Experiments Using Spike-In RNA Variants
DATE: October 19, 2016 TIME: 9:00 AM PT, 12:00 PM ET, 6:00 PM CEST PRESENTED BY:Lukas Paul, PhD Head of Services, Lexogen Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without the use ...
Read More »SIRVs – Spike-In RNA Variant Mixes Designed for Splice Variant Detection
RNA is complex, and its sequencing is even more complex. One of the biggest complications originates from the fact that RNA consists of numerous variations such as alternative splicing and isoforms which are introduced during the process of transcription and ...
Read More »Lexogen has developed Spike-In RNA Variants (SIRVs) for the quantification of mRNA isoforms and begun a test program
Transcript spike-in controls such as the ones devised by the External RNA Control Consortium (ERCC) have been successfully employed in RNA-Seq experiments to assess workflow and platform properties (Munroe et al., 2014). A limitation of these monocistronic, single-gene transcripts is ...
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