RiboDiff – Detecting Changes of mRNA Translation Efficiency from Ribosome Footprints

September 21, 2016 Leave a comment 4,254 Views

Deep sequencing based ribosome footprint profiling can provide novel insights into the regulatory mechanisms of protein translation. However, the observed ribosome profile is fundamentally confounded by transcriptional activity. In order to decipher principles of translation regulation, tools that can reliably ...

SplAdder – Identification, quantification and testing of alternative splicing events from RNA-Seq data

February 10, 2016 Leave a comment 4,889 Views

Understanding the occurrence and regulation of alternative splicing (AS) is a key task towards explaining the regulatory processes that shape the complex transcriptomes of higher eukaryotes. With the advent of high-throughput sequencing of RNA (RNA-Seq), the diversity of AS transcripts ...

RNA-Seq Blog Transcriptome Research & Industry News

Tag Archives: Sloan-Kettering Institute

RiboDiff – Detecting Changes of mRNA Translation Efficiency from Ribosome Footprints

SplAdder – Identification, quantification and testing of alternative splicing events from RNA-Seq data

scRNA-Seq reveals a new type of bone cell that may uncover therapeutic targets for a range of skeletal diseases

DEBKS – a tool to detect differentially expressed circular RNA

Single-cell RNA and protein expression in relation to cell cycle progression

Evaluating capture sequence performance for single-cell CRISPR activation experiments

Seven Bridges Selected by Pfizer to Support Data Management Solution for Single-Cell RNA Sequencing Data

Single-cell mapper (scMappR) – using scRNA-seq to infer the cell-type specificities of differentially expressed genes

Featured RNA-Seq Job – Staff Bioinformatics Scientist, RNA-Seq