RiboDiff – Detecting Changes of mRNA Translation Efficiency from Ribosome Footprints

September 21, 2016 Leave a comment 4,557 Views

Deep sequencing based ribosome footprint profiling can provide novel insights into the regulatory mechanisms of protein translation. However, the observed ribosome profile is fundamentally confounded by transcriptional activity. In order to decipher principles of translation regulation, tools that can reliably ...

SplAdder – Identification, quantification and testing of alternative splicing events from RNA-Seq data

February 10, 2016 Leave a comment 5,256 Views

Understanding the occurrence and regulation of alternative splicing (AS) is a key task towards explaining the regulatory processes that shape the complex transcriptomes of higher eukaryotes. With the advent of high-throughput sequencing of RNA (RNA-Seq), the diversity of AS transcripts ...

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Tag Archives: Sloan-Kettering Institute

RiboDiff – Detecting Changes of mRNA Translation Efficiency from Ribosome Footprints

SplAdder – Identification, quantification and testing of alternative splicing events from RNA-Seq data

SNuBar-ATAC – simple oligonucleotide-based multiplexing of single-cell chromatin accessibility

Single cell RNA sequencing based identification and profiling of Leishmania parasitized host cells

Direct RNA sequencing reveals SARS-CoV-2 m6A sites

Single-cell RNA sequencing identifies of early-stage lung cancer biomarkers from circulating blood

scRNA-seq – Introduction to single cell RNA-seq data analysis

m6A-seq2 – multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution

Scientists use m6A RNA sequencing to gain new understanding of how brain cells talk