Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA–seq

September 28, 2016 Leave a comment 4,221 Views

Cellular heterogeneity can emerge from the expression of only one parental allele. However, it has remained controversial whether, or to what degree, random monoallelic expression of autosomal genes (aRME) is mitotically inherited (clonal) or stochastic (dynamic) in somatic cells, particularly ...

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