Tag Archives: Spatial transcriptomics

Spatial sequencing methods increasingly gain popularity within RNA biology studies. State-of-the-art techniques quantify messenger RNA expression levels from tissue sections and at the same time register information about the original locations of the...

Microbial populations display heterogeneous gene expression profiles that result in phenotypic differences between individual bacteria. This diversity can allow populations to survive under uncertain...

Deciphering the principles and mechanisms by which gene activity orchestrates complex cellular arrangements in multicellular organisms has far-reaching implications for research in the life...

As with real estate, location matters greatly for cells. Douglas Strand confirmed that truth last year when he used a new technique to map gene activity in bladder cancers. Until recently, scientists wanting...

In contrast to whole tissue RNA sequencing, single-cell sequencing has been a promising tool in the research for medical and clinical treatments by analyzing individual cell at its microenvironments and making discoveries of unknown cell types, particularly in rare diseases. ...

Formalin-fixed paraffin-embedded (FFPE) tissues are the most abundant archivable specimens in clinical tissue banks, but unfortunately incompatible with single-cell level transcriptome sequencing due to RNA...

MERFISH platform illuminates biology at the nanoscale to advance discovery and translational research in neuroscience, immuno-oncology, infectious disease/COVID-19 Vizgen, the company developing the next generation of single-cell...

Revealing fine-scale cellular heterogeneity among spatial context and the functional and structural foundations of tissue architecture is fundamental within biological research and pharmacology. Unlike...

Spatial transcriptomics is useful for understanding the molecular organization of a tissue and providing insights into cellular function in a morphological...

Interest in studying the spatial distribution of gene expression in tissues is rapidly increasing. Spatial Transcriptomics is a novel sequencing-based technology that generates high-throughput...