Tag Archives: splicing isoforms

from CoreGenomics by James Hadfield I’m going to start this post by saying something that may be controversial “splicing analysis is a niche, strandedness is useful in a minority of cases and that most RNA-seq users are only interested in ...

Alternative splicing is an important gene regulatory mechanism that dramatically increases the complexity of the proteome. However, how alternative splicing is regulated and how transcription and splicing are coordinated are still poorly understood, and functions of transcript isoforms have been ...