Tag Archives: Stony Brook University

The gene expression approach has provided promising insights into the pathophysiology of posttraumatic stress disorder (PTSD). However, few studies used hypothesis-free transcriptome-wide approach to comprehensively understand gene expression underpinning PTSD. Researchers at Stony Brook University conducted a transcriptome-wide expression study ...

Rob Patro, an assistant professor in the Department of Computer Science in Stony Brook’s College of Engineering and Applied Sciences, leads a group of computational biological researchers that developed a new software tool, Salmon — a lightweight method to provide ...

Technique detects technical biases that otherwise confound test results A new computational method can improve the accuracy of gene expression analyses, which are increasingly used to diagnose and monitor cancers and are a major tool for basic biological research. Researchers ...

The past decade has seen an exponential increase in biological sequencing capacity, and there has been a simultaneous effort to help organize and archive some of the vast quantities of sequencing data that are being generated. While these developments are ...

The alignment of sequencing reads to a transcriptome is a common and important step in many RNA-seq analysis tasks. When aligning RNA-seq reads directly to a transcriptome (as is common in the de novo setting or when a trusted reference ...

Storing, transmitting, and archiving data produced by next generation sequencing is a significant computational burden. New compression techniques tailored to short-read sequence data are needed. Researchers from Carnegie Mellon University and Stony Brook University have devloped an approach to compression ...