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Tag Archives: Structural and Computational Biology

Scientists have identified a set of genomic features will help others to interpret RNA sequencing data

August 20, 2020 Leave a comment 2,721 Views

rna-seq

By studying the genomes of fruit flies, scientists from the Zaugg and Furlong groups at EMBL Heidelberg have identified a set of genomic features that can predict how much the expression of a gene varies between individuals in a species. Their...

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Recent RNA-SEQ Pubs

Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile
25 February 2021
Detection of high heteroplasmy in complete loggerhead and hawksbill sea turtles mitochondrial genomes using RNAseq
25 February 2021
GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression
25 February 2021
Sex-specific expression and DNA methylation in a species with extreme sexual dimorphism and paternal genome elimination
25 February 2021
Single-Cell RNA Sequencing of the Adult Mammalian Heart-State-of-the-Art and Future Perspectives
25 February 2021
Comparative proteomic and transcriptomic analysis reveals high pH-induced expression signatures of Chinese shrimp Fenneropenaeus chinensis
25 February 2021

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


RNA-Seq

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  • rna-seq

    Single-cell mapper (scMappR) – using scRNA-seq to infer the cell-type specificities of differentially expressed genes

    19 hours ago
  • rna-seq

    Featured RNA-Seq Job – Staff Bioinformatics Scientist, RNA-Seq

    20 hours ago
  • Introduction to NGS – RNA-Seq Data Analysis – DNA Variant Calling

    2 days ago
  • rna-seq

    Yale neurologists use RNA sequencing to identify consistent neuroinflammatory response in ICH patients

    2 days ago
  • rna-seq

    Resolve Biosciences’ Molecular Cartography platform detects specific gene expression patterns in SARS-CoV-2 not seen with existing single-cell RNA-seq technologies

    2 days ago
  • rna-seq

    Molecular Stethoscope publishes human proof-of-concept study for its cell-free mRNA based NGS liquid biopsy technology platform

    2 days ago
  • rna-seq

    Simplified Drop-seq workflow with minimized bead loss using a bead capture and processing microfluidic chip

    3 days ago

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