Sample size calculation is a crucial step in study design but is not yet fully established for RNA sequencing (RNA-seq) analyses. To evaluate feasibility and provide guidance, researchers from the Johannes Gutenberg University Mainz evaluated RNA-seq sample size tools identified ...
Read More »EDDA – Experimental Design in Differential Abundance Analysis
High-throughput assays, such as RNA-seq, to detect differential abundance are widely used. Variable performance across statistical tests, normalizations, and conditions leads to resource wastage and reduced sensitivity. EDDA represents a first, general design tool for RNA-seq, Nanostring, and metagenomic analysis, ...
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