Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data

August 1, 2017 Leave a comment 3,004 Views

Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approach identifying novel protein biomarkers. This is especially the case for proteins that differ structurally between disease and control conditions. As tumor development is associated with aberrant splicing, ...

Integration of mass spectrometry and RNA-Seq data to confirm human ab initio predicted genes and lncRNAs

October 28, 2014 Leave a comment 4,833 Views

Tandem mass spectrometry (MS/MS) has been used to improve genome annotation in various organisms. The classical approach is to construct comprehensive theoretical peptide database with six frame translation model from the whole open reading frame (ORF) of a genome, and ...

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Tag Archives: Tandem mass spectrometry

Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data

Integration of mass spectrometry and RNA-Seq data to confirm human ab initio predicted genes and lncRNAs

In Situ RNA Sequencing (ISS) technology will be applied to spatially map cell types for international Human Cell Atlas initiative

Researchers use RNA-Seq to understand how gut bacteria could guard against Parkinson’s

NBSplice – differential splicing analysis based on isoforms expression

3’Pool-seq – an optimized cost-efficient and scalable method of whole-transcriptome gene expression profiling

Effects of control type choices on identifying differentially expressed gene for time-series RNAseq experiments

Technologies to watch in 2020 – Single-cell sequencing

Benchmarking principal component analysis for large-scale single-cell RNA-sequencing