Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data

August 1, 2017 Leave a comment 3,811 Views

Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approach identifying novel protein biomarkers. This is especially the case for proteins that differ structurally between disease and control conditions. As tumor development is associated with aberrant splicing, ...

Integration of mass spectrometry and RNA-Seq data to confirm human ab initio predicted genes and lncRNAs

October 28, 2014 Leave a comment 5,459 Views

Tandem mass spectrometry (MS/MS) has been used to improve genome annotation in various organisms. The classical approach is to construct comprehensive theoretical peptide database with six frame translation model from the whole open reading frame (ORF) of a genome, and ...

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Tag Archives: Tandem mass spectrometry

Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data

Integration of mass spectrometry and RNA-Seq data to confirm human ab initio predicted genes and lncRNAs

Better understand the interactions between DNA, RNA, and protein by using Illumina NGS for multiomic analysis

Researchers uncover the fundamental mechanisms behind the maturation of microRNA molecules

Navigating the unCHARTed – web tool explores public sequencing data for cancer research

BARseq2 – maps neuronal projections paths and gene expression simultaneously

To splice or not to splice…

Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design

New method to add “Time” resolution to your single-cell RNA-seq