Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data

August 1, 2017 Leave a comment 2,762 Views

Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approach identifying novel protein biomarkers. This is especially the case for proteins that differ structurally between disease and control conditions. As tumor development is associated with aberrant splicing, ...

Integration of mass spectrometry and RNA-Seq data to confirm human ab initio predicted genes and lncRNAs

October 28, 2014 Leave a comment 4,513 Views

Tandem mass spectrometry (MS/MS) has been used to improve genome annotation in various organisms. The classical approach is to construct comprehensive theoretical peptide database with six frame translation model from the whole open reading frame (ORF) of a genome, and ...

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Tag Archives: Tandem mass spectrometry

Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data

Integration of mass spectrometry and RNA-Seq data to confirm human ab initio predicted genes and lncRNAs

Clinical utility of RNA sequencing-based testing for thyroid cancer diagnosis and treatment

FASTGenomics – a platform to share single-cell RNA sequencing data and analyses using reproducible workflows

scruff – an R/Bioconductor package for preprocessing single-cell RNA-sequencing data

New single-cell RNA-Seq analysis pipeline available

Application of single-cell RNA sequencing methodologies in understanding haematopoiesis and immunology

New small RNA Sequencing method reveals the first example of cooperation between a plant virus and an insect virus

New Infographic Available – RNA-seq in Neuroscience

RNA-Seq reveals DNA base editing induces substantial off-target RNA mutations