Single-cell RNA-sequencing (scRNA-seq) facilitates identification of new cell types and gene regulatory networks as well as dissection of the kinetics of gene expression and patterns of allele-specific expression. However, to facilitate such analyses, separating biological variability from the high level ...
Read More »Removing technical noise from single cell RNA-Seq data
Single-cell RNA-seq is a promising technology with broad applications and discerning biological noise from technical noise is critical for correctly interpreting the data (Jaitin, et al., 2014). Recently, statistical methods are developed to model the technical noise from spike-in ERCC ...
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